DUf ddlZddlZddlmZddlZddlmZejejddedejd d edej d d ed dej ddddej ddddej dddde dZ dS)N)api)cli cool_path COOL_PATH)metavartypenargs viewpoint VIEWPOINTz--clr-weight-namezxUse balancing weight with this name. Provide empty argument to calculate insulation on raw data (no masking bad pixels).weightT)helpr default show_defaultz-oz --out-prefixz[Save virtual 4C track as a BED-like file. Contact frequency is stored in out_prefix.v4C.tsv)rrequiredz--bigwigzKAlso save virtual 4C track as a bigWig file with the name out_prefix.v4C.bwF)ris_flagrz-pz--nproczQNumber of processes to split the work between. [default: 1, i.e. no process pool])rrr ctj|}tjj|}t j|||r|nd|}|r\||dzddd|r=tj | |j |dz|j d  n%t|ddddS) a Generate virtual 4C profile from a contact map by extracting all interactions of a given viewpoint with the rest of the genome. COOL_PATH : the paths to a .cool file with a Hi-C map. Use the '::' syntax to specify a group path in a multicooler file. VIEWPOINT : the viewpoint to use for the virtual 4C profile. Provide as a UCSC-string (e.g. chr1:1-1000) Note: this is a new (experimental) tool, the interface or output might change in a future version. N)clr_weight_namenprocz.tsv Fnan)sepindexna_repz.bw) value_field)coolerCoolerbioframecore stringopsparse_region_stringr virtual4cto_csv to_bigwigdropna chromsizescolumnsprint)rr r out_prefixbigwigrclrv4cs T/var/www/html/software/conda/lib/python3.11/site-packages/cooltools/cli/virtual4c.pyr$r$ sn - " "C ';;IFFI - ! ! +:D "  C ? :&De LLL     U"KN      cjjTuj==>>> F) rr rclickrcommandargumentstroptionintr$r0r/r9sy    [s!DDD [s!DDD  Z   9   V      * , ,  EDED@, , , r0