tfS ddlZddlZddlmZddlmZddlmZejejde d ejd e d ejd d dejddddddejddejddgdeddZ y)N)util)cli)exit_on_broken_pipe chromsizesCHROMSIZES_PATH)typemetavarbinsizeBINSIZEz--outz-oz Output file (defaults to stdout))helpz--headerz-Hz2Print the header of column names as the first row.TF)ris_flagdefault show_defaultz --rel-idsz-i01ziInclude a column of relative bin IDs for each chromosome. Choose whether to report them as 0- or 1-based.)r rctj|d}tj||}|?|jddj |d<t |dk(r |dxxdz cc<|t j}n t|d}|r|d d j|d d d d |j|d d d d |jy)a Generate fixed-width genomic bins. Output a genome segmentation at a fixed resolution as a BED file. CHROMSIZES_PATH : UCSC-like chromsizes file, with chromosomes in desired order. BINSIZE : Resolution (bin size) in base pairs . T) all_namesNchrom)observedidrwr  F)seplineterminatorindexheader) rread_chromsizesbinnifygroupbycumcountintsysstdoutopento_csvflush)rr outrrel_idsbinsfs ]/var/www/html/software/conda/envs/higlass/lib/python3.12/site-packages/cooler/cli/makebins.pymakebinsr/ s@%%jDAJ << G ,D\\'D\9BBDT w<1  J!OJ { JJ cN  Qq  4E$   KKtDeKLGGI)r%clickrr_utilrcommandargumentstrr$optionChoicer/r0r.r:s &  30AB Y7 gt"DE  =    sCj ! 6 QF8C(r0