o Nrf¢#ã@sXddlZddlZddlZddlZddlZddlmZdd„Zdd„Z dd „Z d d „Z dS) éNé)Ú abs2genomiccCsæt d¡}|j|j}}g}|D]`}dd„| d¡dd…Dƒ}t||ƒ}t |¡ ¡} |jr3| ¡nd} |jr<| ¡nd} | oH| |koH| |k} |  | rPtj ntj ¡}t   | ¡¡ d¡} | | rcdnd |jd œ}| ||f¡q|S) a Retrieve multiple multivec tiles from tids. ---------- filename: string The multires file containing the multivec data tile_ids: [str,...] A list of tile_ids (e.g. xyx.0.0) identifying the tiles to be retrieved Úfloat16cSóg|]}t|ƒ‘qS©©Úint)Ú.0Úirrú_/var/www/html/software/conda/envs/catlas/lib/python3.10/site-packages/clodius/tiles/multivec.pyÚ óztiles..Ú.rérzutf-8Úfloat32)ÚdenseZdtypeÚshape)ÚnpZfinfoÚminÚmaxÚsplitÚget_single_tileÚisnanÚanyÚsizeZastyperrÚbase64Ú b64encodeZravelÚdecoderÚappend)ÚfilenameZtile_idsZf16Zf16_minZf16_maxZgenerated_tilesZtile_idÚtile_posÚmaZhas_nanZma_maxZma_minZuse_f16Z ma_base64Z tile_valuerrr Útiles s$   ýr"c CsÆt|ƒ}t |d¡}|d|d}|d}|d||}|||}tt|dd|ddƒƒ}t||||||d ƒ} t| ƒ|dkr\t | t  |dt| ƒ|d df¡g¡} |  ¡| j S) zî Retrieve a single multivec tile from a multires file Parameters ---------- filename: string The multires file containing the multivec data tile_pos: (z, x) The zoom level and position of this tile ÚrÚ resolutionsrÚ tile_sizerÚchromsÚnameÚlengthr) Ú tileset_infoÚh5pyÚFileÚlistÚzipÚget_tileÚlenrZvstackÚzerosÚcloseÚT) rr ZtsinfoÚfÚ resolutionr%Z tile_startZtile_endÚ chromsizesrrrr r+s  $ÿrc CsV|}g}d}d} d} d} d} tdd„|Dƒ||ƒD]†\} }}tt |||¡ƒ}| ||7} zX|| d}| ||7} |d7}t ||¡}t ||¡}||krTWq |dt|ƒd|||…}| |||7} | | }||kr{|dd…} t|ƒr†| t|ƒ7} Wnty™t  ||df¡}Ynw|  |¡qt  |¡d|d…S) aø Get the tile value given the start and end positions and chromosome positions. Drop bins at the ends of chromosomes if those bins aren't full. Parameters: ----------- f: h5py.File An hdf5 file containing the data chromsizes: [('chr1', 1000), ....] An array listing the chromosome sizes resolution: int The size of each bin, except for the last bin in each chromosome. start_pos: int The start_position of the interval to return end_pos: int The end position of the interval to return Returns ------- return_vals: [...] A subset of the original genome-wide values containing the values for the portion of the genome that is visible. rcSsg|]}|d‘qS)rr)r Úcrrr r „r zget_tile..rr$ÚvaluesNéÿÿÿÿ) rrrÚceilÚmathÚfloorÚstrr/Ú IndexErrorr0rZ concatenate)r3r5r4Ú start_posÚend_posrZbinsizeZarraysÚcountZcurrent_binned_data_positionZcurrent_data_positionZ num_addedÚ total_lengthZcidÚstartÚendZn_binsZchromÚxÚoffsetrrr r.WsB       € û r.c Cs¦t |d¡}tdd„|d ¡Dƒƒddd…}dg}tt|dd dd…ƒƒg}t|d jd ƒ}|dd d}t|dt|dƒd |j ƒ}||d<|||||dœ}d|dt|dƒjvr¸|dt|dƒjd} t | dƒtkr™z dd„| Dƒ|d<WnGt j y˜dd„| Dƒ|d<Yn5wz dd„| Dƒ|d<Wn(t j y·dd„| Dƒ|d<Ynwd|d vrÍ|d dd} t   | ¡|d<| ¡|S)aO Return some information about this tileset that will help render it in on the client. Parameters ---------- filename: str The filename of the h5py file containing the tileset info. Returns ------- tileset_info: {} A dictionary containing the information describing this dataset r#cSrrr©r r#rrr r êr z tileset_info..r$Nr8rr&r(Úinfoz tile-sizer'r7)r$Úmin_posÚmax_posr%rÚ row_infoscSsg|]}t |¡‘qSr)ÚjsonÚloadsrFrrr r ócSsg|]}|‘qSrrrFrrr r scSsg|] }t | d¡¡‘qS©Úutf8)rKrLrrFrrr r sÿcSsg|]}| d¡‘qSrN)rrFrrr r rMr)r*r+ÚsortedÚkeysrÚsumÚattrsr,r<rÚtyperKÚJSONDecodeErrorrLr1) rr3r$rHrIr%Z first_chromrr)rJZrow_infos_encodedrrr r)ÓsD $"ûÿÿÿ r)) rrKr:r*ÚnumpyrÚutilsrr"rr.r)rrrr Ús  , |